Initial negotiations after Astron's merger with Tactica have led to nine staff at Tactica's Norwich headquarters taking redundancy.
Group operations director Kathy Woodward said the firm had declared 34 Norwich-based jobs "at risk", and negotiations had begun immediately with three unions.
"There are some opportunities for people to transfer, but to be honest that's not too attractive for staff in Norwich, and I expect a number of redundancies not dissimilar [to 34]," said Woodward, who added that negotiations had gone "as well as they could ever go".
"It's part of the migration of the head office to Huntingdon," added chief executive David Mitchell.
The redundancies are in head office functions like marketing and finance, but group purchasing and customer service for some of its largest contracts will stay in Norwich.
Have your say in the Printweek Poll
Related stories
Latest comments
"And here's me thinking they bought the Docklands Light Railway."
"15 x members? Why don't they throw their lot in with the Strategic Mailing Partnership (SMP) and get a louder voice?"
"Some forty plus years ago I was at a "sales" training seminar and got chatting to the trainer after the session had finished.
In that conversation he told me about another seminar he had..."
Up next...
Customer demand increasing
A4 Laser Labels expands with larger site and kit investment
Price rises in US 'to at least partially offset' costs
Cimpress withdraws guidance due to Trump's tariffs
Proceeds to be invested in growth strategy
James Cropper sells some specialist IP
Making changes to limit tariff impact in US