It is likely that the losses will be from the groups operations in the UK, Ireland and South Africa, as its businesses in New Zealand and Australia have already been heavily restructured.
Independent News & Media said that it plans to remove duplication across its pre-press, editorial and clerical operations, although no specific details are available.
The company is also considering moving some of its facilities to cheaper locations. The restructuring will have a one-off charge of 37.5m.
Independent News & Media employs 800 in the UK, 1,200 in Ireland and 3,000 in South Africa.
Last week the group sold its London-based regional operations to Argent Regional for 62m.
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